本期推荐：研究团队针对炎症性疾病中eNAMPT异常分泌的调控机制展开攻关，发现LPS通过NLRP3炎症小体激活NEDD4介导的NAMPT泛素化 ...

本文聚焦乙肝病毒（HBV）感染引发的肝脏疾病，通过多种模型研究发现，HBV 经 ATR 激活 NAMPT，后者与 INSR 作用促使肝星状细胞（HSC）活化，推动肝纤维化和肝细胞癌（HCC）进展。抑制相关通路可缓解病症，为 HBV 相关肝病治疗提供新方向。 乙肝病毒感染相关肝脏 ...

Remedy Plan Therapeutics has commenced dosing in a randomised Phase I trial of hyperbolic nicotinamide phosphoribosyltransferase (NAMPT) inhibitor, RPT1G, for cancers. RPT1G is designed to target ...

ConferenceHeidelberg Pharma to Present Data from its ADC Technology Platforms at AACR Annual Meeting 2025 26.03.2025 / 09:23 CET/CESTThe issuer is solely responsible for the content of this ...