在生物学研究中，大肠杆菌 NADPH 依赖型同化亚硫酸盐还原酶（SiR）的亚基结合机制长期未知。为解决此问题，研究人员开展 SiR 的结构研究。他们利用特殊技术确定了最小异源二聚体复合物的近原子分辨率结构，揭示了亚基结合界面，为相关研究提供关键信息。

为验证NOX2/ROS轴的治疗潜力，研究团队在DSS诱导的结肠炎和牙周炎小鼠模型中使用了NOX2抑制剂。结果显示，NOX2抑制剂显著减轻了牙周炎引起的牙龈肿胀、炎症和牙槽骨破坏（图6）。活体成像和免疫荧光染色进一步证实，NOX2抑制剂显著降低了牙周组 ...

1 Temporal changes in the levels of NADPH and ATP, which play an essential role in many biochemical reactions inside the cell, indicated that certain metabolic pathways are differentially active at ...

First of all, in the so-called light-driven reaction, light energy is converted into chemical energy that the plant can use ...

In addition, the cells use an NADPH oxidase (an enzyme in the cell membrane) to release reactive oxygen species as further ...