Did you know that you have a second genome? Small cellular organelles called mitochondria contain their own circular DNA. What happens to your cells when this DNA mutates? Similar to the nuclear ...
What causes age-related declines in mitochondrial ... disease be prevented or reversed, and does that alter CVD risk? 18. How clinically effective and safe are lifestyle interventions in older adults?
But while constraint models have been highly effective for identifying disease-causing variants in the nuclear genome, they have not been useful for mutations in the mitochondrial genome ...