Did you know that you have a second genome? Small cellular organelles called mitochondria contain their own circular DNA. What happens to your cells when this DNA mutates? Similar to the nuclear ...
"Results of our prospective study of 22 adults and 38 children with confirmed primary mitochondrial disease revealed that the ...
But while constraint models have been highly effective for identifying disease-causing variants in the nuclear genome, they have not been useful for mutations in the mitochondrial genome ...
Mitochondrial diseases are a group of genetic disorders characterized by mutations in nuclear or mitochondrial DNA, causing a range of manifestations that can present at various times. This ...
What causes age-related declines in mitochondrial ... disease be prevented or reversed, and does that alter CVD risk? 18. How clinically effective and safe are lifestyle interventions in older adults?
conducted the study to determine the diagnostic impact of genomic sequencing using blood samples from those with ...
Researchers at Case Western Reserve University and Mass Eye and Ear will study what causes acquired hearing loss (AHL) and ...