However, it remains unknown whether deleterious gliosis and phenotypically aberrant glia in ALS are causally associated with the emergence of senescent cells in the degenerating spinal cord. In this ...

We found that the cell-based prediction significantly outperformed an approach in which the population-level time in culture was used as a classification criterion (96% vs 86%, respectively). In mixed ...

Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...

Glial Cultures,BDNF Expression,Biological Sex,Brain Aging,Cell Culture,Cell Types,Cellular Energy,Culture Vials,Differentially Expressed,Differentially Expressed ...

Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and ...

Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and ...

Researchers suspected that microglia could also break down amyloid plaques, but it was unclear how the cells could consume these massive aggregates, which are much bigger than they are. "We found ...

1 Department of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China 2 Jiangsu Key Laboratory of Neuropsychiatric ...

Microglia, the brain's immune cells, exhibit altered gene expression and a weakened immune response as they age, potentially contributing to neurological disorders like Alzheimer's and Parkinson's.

The new study takes cell culture research a step further ... Alzheimer’s disease to show that xenon changes the behavior of microglia, an immune cell that can be found in the spinal cord ...