Even well-known drugs can cause entirely unpredictable effects on metabolism, Swiss researchers have shown. Rapidly mapping ...

However, mechanistic studies to support the conclusion that mitochondrial function is increased in the tumours remain incomplete and would benefit from experiments that would directly interrogate ...

Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, ...

The question of how intestinal commensals adapt their metabolism to daily nutrient fluctuations has therefore become a central topic of microbiota research. At the heart of this network is the RNA ...

The GENRE collection, termed PATHogen GENome-scale Network reconstruction ... which are linked to drug metabolism and antimicrobial resistance. The analysis also showed that the clustering ...

Thousands of metabolic pathways exist and most involve multiple steps – some can be hundreds of steps long! All metabolic pathways together form a complex network that is necessary to maintain life.

The MEP pathway is an essential part of the energy metabolism of several bacteria, including the hospital germ Pseudomonas aeruginosa. If the MEP pathway in bacteria is blocked, for example by a ...