研究人员分析 470 例 ALS 患者全外显子测序数据，发现 MAPT 突变与 ALS 相关，该成果意义重大。 探索神经退行性疾病的神秘关联：MAPT 突变与肌萎缩侧索硬化 在神经科学的领域中，肌萎缩侧索硬化（Amyotrophic Lateral Sclerosis，ALS）和额颞叶痴呆（Frontotemporal Dementia ...

研究人员针对额颞叶痴呆（FTD）等疾病，解析 MAPT 突变 V337M 和 R406W 的 tau 丝结构，发现其呈阿尔茨海默折叠。 在神经退行性疾病的研究领域，额颞叶痴呆（FTD）和阿尔茨海默病（AD）是最常见的早发性痴呆类型。FTD 以行为改变为首发症状，随后才出现认知障碍 ...

Paul Atkins, President Donald Trump's pick to lead the Securities and Exchange Commission, was questioned by the Senate Banking Committee on Thursday as part of his confirmation process. In the ...

A Medicaid asset protection trust (MAPT) can be useful for estate planning if you believe you or your spouse will need ...

We have developed a series of targeted mice expressing frontotemporal-dementia-causing mutations in the humanized MAPT gene to investigate the earliest stages of tauopathy." Tau ...