Lissencephaly is a spectrum of rare, genetic disorders in which the brain fails to develop its hallmark folds. The disorders ...

Yale researchers identified an underactive mTOR pathway as a cause of lissencephaly and reversed brain malformations in ...

The findings, reported Jan. 1 in Nature, may point to a target for treatment, researchers say. "Lissencephaly belongs to a ...

“Lissencephaly belongs to a group of disorders we call malformations of cortical development, meaning the normal development and structure of the brain is disrupted,” said Angeliki ...

Every birthday is more special than the last for Amber McCreary, but it wasn’t always that way. After turning 29 years old on ...

"Lissencephaly belongs to a group of disorders we call malformations of cortical development, meaning the normal development and structure of the brain is disrupted," said Angeliki Louvi ...

The findings, reported Jan. 1 in Nature, may point to a target for treatment, researchers say. “Lissencephaly belongs to a group of disorders we call malformations of cortical development, meaning the ...

They are caused by rare mutations in select genes that are important for brain development. Lissencephaly spectrum disorders are a rare group of genetic disorders characterized by a lack of ...