The hormone leptin was discovered 30 years ago to much fanfare. Scientists hoped that leptin, which regulates body fat, could pave the way for obesity treatments. The results in mice were hailed ...

Researchers from the School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry.

Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of ...

Initial information on the newly discovered hormone leptin suggests a primary role in energy balance and body weight maintenance. Recent published information suggests that leptin has an impact on ...

A significant aspect of obesity is the development of leptin resistance, primarily due to the inefficient transport of leptin across the blood-brain barrier and other mechanisms such as protein ...

In humans, many leptin deficiency syndromes are responsive to leptin replacement therapy. As leptin is involved in numerous pathways, the effects of too little leptin are widespread (including ...

Leptin is a hormone that plays a key role in regulating your appetite and body weight. It's responsible for signaling to the ...