qPCR 和 Western blot 分析发现，感染后 ATG7 mRNA 和蛋白表达上调，自噬底物蛋白 p62 水平下降，LC3-II/LC3-I 比值升高，表明 BVDV 感染可诱导 MDBK 细胞自噬，且呈时间依赖性。 Bta-miR-221 介导的 ATG7-LC3 自噬通路：激光共聚焦显微镜观察到 LC3 主要位于细胞核，ATG7 位于细胞 ...

Cold plunges have become a fixture on wellness feeds and gym schedules. But what does science say when you strip away the ...

S. Pankiv et al., “p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy,” J Biol Chem, 282:24131–45, 2007. (Cited in 113 papers) Terje ...