A renal biopsy was then pursued, which confirmed amyloidosis on electron microscopy; however, no immune complex or light chain deposition was identified. Mass spectrophotometry of nerve and kidney ...

This study sought to develop selection guidelines to determine the eligibility for SCT of patients with light-chain amyloidosis. Patients with biopsy-confirmed ... with renal and cardiac amyloid ...

but rarely presents as progressive renal failure. The heart is affected pathologically in up to 90% of systemic AL amyloidosis patients, which represents the most important clinical manifestation ...

Because the blood–brain barrier may pose a particular challenge for the delivery of large, protein-based therapies, Amyl’s focus is currently on systemic amyloidosis diseases. Amyl ...