The Cambridge team designed the sensor by combining two key components: ・Polydopamine (PDA): A stable, biocompatible material that serves as a platform for detecting senescent cells. ・Indocyanine ...

A study in Scientific Reports evaluated a photoacoustic polydopamine-indocyanine green (PDA-ICG) nanoprobe for detecting senescent cells. Senescent cells play a role in tumor progression and ...

ICG binds to plasma proteins, allowing it to be absorbed by liver cells. Due to the impaired bile excretion function of HCC cells, ICG tends to accumulate in tumor tissues, making them detectable ...

Myeloid lineage cells, including macrophages ... popliteal LNs and footpad of TNF-Tg mice with established arthritis by ICG-NIR fluorescent imaging. A dose of 1 µg/10 µl ICG was intradermally ...