Obviously, this is not an option in humans. “The only thing you can do for human iPSCs is take that cell line and put it into a teratoma assay in a mouse, and ask if the tumor tissues that form ...

But the impact of iPSCs on drug discovery has been frustratingly modest. “Everyone thought that stem cells were going to give us the human cell models that we required to make better drugs ...

Ncardia’s iPSC-derived microglia may aid ALS research and help to screen new therapies that target inflammation in ALS.

Pluristyx has developed a clinical-grade manufacturing process for using a licensed Mad7 gene editing technology to block Human Leukocyte Antigen (HLA) markers expression. Humacyte is optimizing a ...

H uman induced pluripotent stem cells (iPSCs) have a great potential for scientific and medical applications. They are used in research laboratories to model human diseases, helping to uncover ...

derivation of functional dopamine neurons from various cell sources including human ES cells, based on the strategy of cell replacement therapy to parkinson’s disease, and ii) specific gene functions ...

Differentiation of iPSCs into neurons, astrocytes and microglia allow us to analyze aberrant gene and protein expression, function and metabolism in developing and maturing human brain well before the ...

First, the team developed human iPSCs that glow when exposed to a specific wavelength of light if they have the ...

Derived by reprogramming adult cells, such as skin and blood cells, back to an embryonic-like state, iPSCs can differentiate into many types of cells in the human body. Moreover, iPSCs can be created ...