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HOXC6 与 M2 巨噬细胞 “狼狈为奸”:MSI-H 结直肠癌转移及免疫逃逸的 ...
HOXC6 在 MSI-H CRC 中过表达且与不良预后相关 :研究人员分析 TCGA 和 GSE39582 数据集发现,HOXC6 在 MSI-H 的右侧结肠癌(RCC)中比在微卫星稳定(MSS)的 RCC 和左侧结肠癌(LCC)中表达更高。进一步研究表明,高表达 HOXC6 的 MSI-H CRC 患者临床结局更差。
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