Mnl1 demannosylates misfolded, globular proteins and Pdi1 then reduces the disulfides to generate unfolded proteins competent for ERAD. This study expands the molecular grammar of FUS, identifying ...

While proteins are long, spiral molecule chains ... They are strong and are generally insoluble in water. Globular proteins are molecules involved in the regulation of life processes.

Actin is a globular protein that is a major constituent of the cellular cytoskeleton. Actin can exist in monomeric form as G-actin (globular actin) or can form filaments (F-actin, filamentous ...