Employing its deep understanding of G-protein coupled receptors (GPCRs) the Beacon Discovery team has delivered more than 20 compounds into clinical development over the past two decades ...

A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these receptors, including ...

Cell membrane proteins hide secret gateways that can be used to modify cell behavior. This has been demonstrated in a study ...

A new study shows how common gut bacteria can metabolize certain oral medications that target cellular receptors called GPCRs, potentially rendering these important drugs less effective.

A study published in Nature Chemistry by researchers from the University of Pittsburgh and Yale University shows how common ...

Bacteria in the gut could make certain medicine less effective, researchers say - Researchers say these findings could help ...

G Protein-Coupled Receptors (GPCRs) in advancing GPCR-targeted therapies, including the use of agonists, antagonists, biased ...

While this has been well established, the dimerization of G-protein coupled receptors (GPCRs) (that represents ∼1% of the genes present in a mammalian genome) has not been well documented until ...

Previously unknown access points in cell membrane proteins have been discovered, enabling laboratory-developed drugs to modify cell function. The discovery was made possible through computer ...

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments—water, lipid membranes, or other condensed phases—are critical to their ...

Common gut bacteria can metabolise some oral medications potentially rendering these important drugs against migraines, ...