While this has been well established, the dimerization of G-protein coupled receptors (GPCRs ... came from studies with non-functional GABA B receptors that dimerize to generate a functional ...

The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...

Arbaclofen is under clinical development by Allos Pharma and currently in Phase II for Unspecified Genetic Disorders.