Patients with acromegaly make too much growth hormone, which causes them to grow disproportionately large bones, organs and ...
The most constant radiological features of acromegaly include soft tissue hyperplasia, and increased joint spacing, especially in the limbs by articular cartilage overgrowth. Overgrowth is ...
Acromegaly is associated with increased mortality, mostly attributed to cardiovascular, cerebrovascular and respiratory abnormalities. 1 Tight biochemical control of the growth hormone axis is ...
Biochemical control of acromegaly in noncured patients is usually defined as serum growth hormone (GH) levels <2.0 µg/l, plus normal-for-age serum levels of insulin-like growth factor I (IGF-I).
Crinetics Pharmaceuticals, Inc. (Nasdaq: CRNX) today announced the U.S. Food and Drug Administration (FDA) accepted its New Drug Application (NDA) for investigational ...