They do all this by binding to a receptor called FXR, which acts like a traffic light, controlling cholesterol metabolism and bile acid production to avoid excess buildup." Here's where the ...

Scientists have known for some time that gut bacteria modify bile acids into a form that stimulates a receptor called FXR, which reduces bile production. The new study, published Jan. 8 in Nature ...

This disruption affects the signaling pathway involving FXR, which normally regulates bile acid synthesis and intestinal ...

University of Wisconsin–Madison researchers revealed how gut microbial bile acids impact colon cancer. One bile acid slows tumor growth by supporting the FXR protein, while another accelerates cancer ...

Farnesoid X receptor agonists: Inhibit bile acid synthesis and promote bile flow, offering a new therapeutic target for various cholestatic conditions. Significant progress has been made in ...

Scientists have known for some time that gut bacteria modify bile acids into a form that stimulates a receptor called FXR, which reduces bile production. The new study, published Jan. 8 in Nature ...

When gut bacteria produce large amounts of bile acids that activate FXR and reduce bile production, the body counteracts by producing BA-MCY. This prevents a slowdown in fat metabolism and ensures ...