Embryologist Conrad Waddington coins the term “epigenetics” to describe the developmental processes that connect an organism’s genotype to its phenotype. The term will later be coopted to describe ...

Evidence is mounting that epigenetic marks on DNA can influence future generations ... selection to produce a population where all individuals bear the same beneficial phenotype if that trait were ...

Despite such uncertainties, this epigenetic mechanism clearly demonstrates how profoundly environment can affect gene expression and phenotype in a long-lasting way.

In general, when we know that the genotype is present but the phenotype is not observable ... to protein activation is known as an epigenetic factor. Indeed, there are multiple points at which ...

Oncology, titled "Tumor Metastasis: Mechanistic Insights and Therapeutic Intervention," a research team from Guangzhou ...

Dr. R. L. Jirtle, [3] of the Duke University Medical Center, Durham, North Carolina, discussed the effects of fetal nutrition on epigenetic phenomena, and their influence on adult disease ...

Chromosomal inversions induced by CRISPR/Cas in Arabidopsis thaliana show that the epigenetic state and gene expression remain largely stable, with only 0.50–1% of genes differentially expressed.

Maternal stress could leave epigenetic imprints on genes in the placenta associated with cortisol — a necessary hormone for fetal development — and this would affect the baby's development ...

These epigenetic modifications may substantially affect cell function, defining the phenotype of each cell. Therefore, this ...

Future research will focus on unraveling the intricacies of gene regulation, epigenetic mechanisms, and the role of non-coding DNA in shaping the genotype. The exploration of gene-gene interactions ...

Epigenetics of Fetal Alcohol Spectrum Disorders (epiFASD ... Owing to the complex, highly variable phenotype and lack of proper diagnostic tools, FASD is severely underdiagnosed. The purpose of the ...