There is a growing awareness that epigenetic dysregulation plays a significant role in many types of cancer, and that is fuelling an increasing number of studies into drugs that target epigenetic ...

Imprinted gene dysregulation can also occur in somatic cells, either by epigenetic or genetic mutations, causing cancer (39,40). Furthermore, only a single event is required to completely ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

demonstrating a close relationship between epigenetic dysregulation and the pathogenesis of autoimmune-related skin disorders ...

Additionally, epigenetic dysregulation has been implicated in a wide variety of neurological disorders 1,7. Neuroepigenetics promises to be an exciting and productive area of inquiry as we continue to ...

demonstrating a close relationship between epigenetic dysregulation and the pathogenesis of autoimmune-related skin disorders ...

Basically, this epigenetic dysregulation of gene expression is at the top of a domino effect that affects cellular function and other degenerative processes. So underlying a great deal of modern ...

The Luo Lab is interested in developing and leveraging novel approaches at the interface of chemistry and biology to annotate functional roles of epigenetic modulators. Epigenetic regulation is ...

This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

C. miRNA and epigenetic effects interact to form a miRNA-epigenetic feedback loop, whose dysregulation is closely related to cancer development. D. miRNA dysregulation forms a complex tumorigenic ...