The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

Genes make up the blueprints and outline the process of building every living organism. To ensure that the right genes are ...

Healthcare - The exploration of peptides as bioregulatory molecules has gained considerable attention in recent years, with a ...

Rosalind Franklin, James Watson and Francis Crick discovered the structure of DNA -- that molecular blueprint for life -- over 70 years ago. Today, scientists are still uncovering new ways to read it.

The findings also revealed that DNA can be repaired by cooperation between repair proteins. These proteins organize themselves into "hubs," where multiple damaged DNA regions come together. These ...

Epigenetic modifications, such as DNA methylation and histone modifications, can affect gene expression by altering the accessibility of DNA to transcription factors and other regulatory proteins. DNA ...

For pregnant women, exposure to fine particulate air pollution (PM2.5) was associated with altered immune responses that can lead to adverse birth outcomes, according to a new study led by Harvard T.H ...

Our group retains an interest in the areas of structure-function studies of RNA interference mediated by siRNA pathway, and on post-translation histone and DNA modifications impacting on epigenetic ...

Some DNA viruses use cellular histone proteins to compact their genomes whereas others use small basic molecules. Adenoviruses encode their own histone-like protein, called protein VII, that forms a ...

If DNA damage is not properly repaired, mutations can occur, which may result in diseases like cancer. Cells use repair systems to fix this damage, with specialized proteins locating and binding ...