UCLA Health researchers say study findings uncover Huntington's disease mechanisms and pave new ways to develop treatments.

First, the study tested 6 DNA mismatch repair genes and only four of them appear to strongly (Msh3 and Pms1) or moderately (Msh2 and Mlh1) modify pathogenesis in HD mouse model. Interestingly ...

This played a key role in mapping the HD gene (Gusella et al., 1983). Although researchers had discovered that the G8 DNA probe was likely to correspond to a polymorphic chromosomal region located ...

A new CRISPR-based technology, called RIDE, is a leap forward for this trail-blazing technology. With the precision of a ...

The DNA vaccine, owned by private biotechnology company Technovalia, and delivered by Vaxxas’ HD-MAP, generated a significant antibody response in mice against multiple domains of the spike ...