Recent draft guidance highlights the challenges that industry and regulators face to predict rare drug-induced liver injury. At the end of August 2008, the consultation period ended for comments ...
If so, then subpopulations that are sensitive to hepatotoxic effects of specific drugs could be identified, along with biomarkers of susceptibility, and the 'selectively hepatotoxic' drugs could ...
Drug-induced liver injury (DILI) is common because it can be caused by different pharmacological agents from nearly all classes of medications, including hepatotoxic drugs, anesthetics, anticancer ...