Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, ...

The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

近日，中国科学院微生物研究所刘晓团队在Nucleic Acids Research上发表了题为“Checkpoint kinases regulate the circadian clock after DNA damage by influencing chromatin ...

A recent study has shed light on the transcriptional regulatory mechanisms of Penicillium expansum, the fungal culprit behind ...

In eukaryotes, genomic DNA is stored in the nucleus as nucleosomes, interacting with a set of proteins, forming a molecular complex called chromatin. The proper folding of the chromatin structure ...

CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

A novel technique to visualize gene-active and gene-repressive DNA regions in living cells, developed by a ...

Now, for the first time, EMBL scientists have directly observed this process in high resolution under the microscope using a new chromatin tracing method. The new study shows that the long DNA ...