These signalling systems operate beyond cell and tissue boundaries, but function as morphogens that are secreted from one cell or tissue type to activate surface receptors, signal transduction ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...

The researchers next showed that when macrophages were exposed to inflammatory signals, their activity changed alongside ...

Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Types of cell signalling pathways ...

The mammalian immune system is an evolutionary wonder. It's capable of recognizing and destroying cancer cells, and it can ...

Cell-free systems, which can express an easily detectable protein with a DNA or mRNA template without constraints of living ...

In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most ...

My group focuses on understanding cell signaling pathways primarily linked with the ubiquitin and autophagy systems and frequently altered in diseases, including neurodegenerative disease. To this end ...

Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, ...

A new study in the peer-reviewed journal Stem Cells and Development describes the development of a co-culture system of ...

The lobate shape of lymphatic endothelial cells puzzled researchers—now they’ve found it helps stabilize lymphatic ...

The controlling mechanism behind these protein complexes is fundamental to our knowledge of protein signaling pathways and the physiological responses they control. The poster focuses on the pivotal ...