Spectacular progress has been made in our understanding of the physical processes that underlie the functions and mechanisms of cytoskeletal proteins. For example, the atomic structures of actin ...
The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...
Similarly to mice that lack other regulators of the cytoskeleton, HEM1-deficient T cells showed decreased activation and proliferation compared with wild-type T cells. Surprisingly, some T-cell ...
In addition, in immune cells, the cytoskeleton is essential for phagocytosis. Following the advances in proteomics technology over the past two decades, cytoskeleton proteome analysis in resting ...
Proteomics Approaches to Analysis of the Cytoskeleton in Immune Cells Cytoskeletal proteins are often identified in many proteomic studies either as contaminants, owing to their very high ...
The discovery opens the door to healthier aging in humans. The cytoskeleton provides most cells with their shape, structure, and internal organization. In turn, the cytoskeleton relies on a type ...
In our lab, we aim to elucidate the interplay of clathrin structures with the actin cytoskeleton and cellular adhesions ... To tackle these questions, we use a multidisciplinary approach combining ...
We aim to understand the molecular logic behind the dynamics of the actin cytoskeleton at endocytic sites and how disturbances in this process affect physiology and disease progression. Leonardo is ...
Images of an anaphase cytoskeleton in a dividing cell (left) and when rebuilt in vitro (right). PRC1 (green) crosslinks microtubules and organises compacted microtubule bundles. A living cell is a ...