For example, the commonly used Cas9 is about 1,400 amino acid residues long ... The team observed a 4.4-fold increase in the editing efficiency of this modified nuclease, surpassing most of the ...

Alongside CRISPR/Cas9 and TALEN, zinc finger nuclease is an important tool in the field of genome editing. Engineered to break certain bonds within the polynucleotide chain of a DNA molecule ...

A revolution in biomedicine is currently underway, driven by the application of genome engineering tools such as the ...