Capecitabine (Xeloda ™; Roche ... is converted in a final catabolic step to fluoro-beta-alanine (FBAL); this metabolite has been the focus of many pharmacokinetic publications, which have ...
Herrmann et al. compared the safety and efficacy of gemcitabine plus capecitabine (GemCap) with that of gemcitabine monotherapy in patients with pancreatic cancer. This phase III trial included ...
The article by Graetz et al entitled “Leveraging Mobile Health to Improve Capecitabine Adherence Among Women With Breast Cancer: A Pilot Randomized Controlled Trial” (JCO Oncology Practice ...
During the first cycle of capecitabine development, three concomitant drugs were found to affect 5-FU clearance. [5] Paracetamol and morphine increased 5-FU clearance by 26% and 41%, respectively ...
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