Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

Here, we combine cytosine and adenine base editors and a prime editor to assess the pathogenicity of a broad spectrum of ... cause a healthy cell to transform into a cancer cell or make a cancer ...

This approach is called "immune checkpoint blockade." Mutations are alterations in the genetic code that can lead to cancer. All cancers fall on a spectrum, depending on how many mutations the cells ...

Spectrum filed for accelerated approval of poziotinib as a second-line treatment for patients with HER2 exon 20 insertion-mutated, non-small cell lung cancer (NSCLC), but the FDA was unconvinced ...

The Centenary Institute has received important funding from the RT Hall Trust to bolster two ground-breaking cancer research initiatives. Almost one ...

High Efficacy of SLS009 Observed in 67% of ASXL1 Mutated Solid Cancers vs 0% in Non-ASXL1 Mutated Cancers – - ASXL1 Mutations Predictably Identified in Colorectal Cancer (CRC MSI-H) and Non-Small Cell ...