Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup. Researchers at RPTU University Kaiserslautern-Landau, Southwest Germany, have ...

The nucleus is the compartment within each cell that contains the genetic information directing how the cell grows and behaves. Large cells generally have large nuclei, while smaller cells have ...

How does PAT-DX1 target cancer cells? PAT-DX1 targets tumors ... PAT-DX1 then penetrates the cell nucleus where it binds to sites of damaged nuclear DNA, inhibiting DDR processes (Fig.

Stanford researchers have conducted the first large-scale screen of these inherited changes, called single nucleotide variants, and homed in on fewer than 400 that are essential to initiate and drive ...

A pioneering study by scientists from the University of Cyprus and the University of Oxford has uncovered a new cellular ...

In a recent trial, researchers found that Xpovio plus chemo had activity in NSCLC patients with KRAS mutations other than ...

But cancer cells also cross established boundaries ... a dynamic scaffold of filaments and tubes that extends from the cell nucleus to the cell membrane. In addition, myosins reduce the activity ...

Cancer cells eventually mutate to resist treatment, so understanding this process can give researchers a clue into how these cancer cells defend themselves. Trotman used single-nucleus whole-genome ...