Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Discover how next-generation kinase inhibitors are transforming clinical therapy byovercoming resistance and enhancing ...

Stomach cancer forms electrical circuits with nerves to fuel its growth, which could be disrupted using migraine drugs.

Scientists at VCU Massey Comprehensive Cancer Center have identified an innovative combination of treatment strategies that ...

Pancreatic cancer is fueled by connections to the nervous system. This is reported by scientists from the German Cancer ...

Cancer cells have recently been shown to collaborate to obtain vital nutrients from their environment, a phenomenon that was ...

Research uncovers tumor cell cooperation via CNDP2, suggesting new therapeutic strategies that disrupt nutrient sharing to ...

Researchers have found that a cancer outside the brain makes electrical connections with the nervous system to fuel cancer growth and aid its spread.

Researchers have discovered that stomach cancers make electrical connections with nearby sensory nerves and use these ...

Pancreatic cancer reprograms nerve cells to fuel its growth, but blocking these connections can shrink tumors and boost ...

"The result underscores that both types of nerve cells have functional relevance for tumor growth," explains Vera Thiel.