本研究深入剖析了CTCF（CCCTC结合因子）突变对基因调控和染色质结构的影响，揭示了其在癌症和神经发育障碍中的潜在作用机制。 CTCF（CCCTC结合因子）是一种在基因调控中发挥关键作用的转录因子，其通过与染色质结合形成拓扑关联域（TAD）结构，限制调控元件 ...

A federal judge agreed last week that an incarcerated man's claims could proceed against two state corrections employees, ...

Another protein, CTCF, attaches to locations of super-enhancer DNA and pairs them up with genes that they will later turn on during sperm development. This sets up a new structure that cements the ...