为探究 CD8 + 肿瘤浸润淋巴细胞（TILs）对乳腺癌预后的影响，研究人员开展相关荟萃分析。结果显示，高 CD8 + TIL 密度与患者良好预后相关，且不受其位置影响。该研究为乳腺癌免疫治疗提供依据。

沉默KLF2促使CD8 T细胞沿着不同的分化路径发展，引导它们远离杀伤性T细胞，进入一种称为衰竭的功能失调状态，这种状态会降低这些细胞对抗感染和 ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

TGF-ß signaling is known to promote immune exclusion, where CD8 + T cells are in the surrounding stromal tissue but not within the tumor itself. To better identify patients who are immune ...

CD8 + T-cells are cytotoxic immune cells that can kill cancer cells, as well as cells infected with viruses or bacteria. These specialized T-cell express receptors that recognize specific antigens ...