为探究 CAR 设计对 NK 细胞的适用性，研究人员对比 CD28 和 4-1BB 共刺激，发现 CD28 更优，为 CAR-NK 疗法提供新思路。 在肿瘤治疗的战场上，免疫疗法近年来可谓大放异彩，其中嵌合抗原受体 NK 细胞（CAR-NK）疗法更是潜力无限。它就像给 NK 细胞（自然杀伤细胞 ...

These recipients were then used to compare cytokine responses to three different antibody-based therapies known to stimulate cytokine release, including muromonab-CD3 (OKT3), anti-CD28 and an ...

GMP ActiveMax ® Human T Cell Activation/Expansion CD3/CD28 Beads are uniform 5.5 μm magnetic beads coated with an optimized mixture of GMP-grade mouse monoclonal antibodies targeting CD3 and ...

Conventionally, the first and second stimulation signals in vitro, simulating the process in vivo, are achieved using anti-CD3 antibody, anti-CD28 antibody, or CD3/CD28 magnetic beads, along with the ...

Third Arc Bio also announced ongoing progress in its Synergy Platform, driving new multispecific antibody programs targeting ...

Novel trispecific T cell engager, ZW209, demonstrates potent preclinical efficacy against DLL3-expressing tumors and an encouraging safety profile VANCOUVER, British Columbia, March 25, 2025 (GLOBE ...