为探究 CAR 设计对 NK 细胞的适用性,研究人员对比 CD28 和 4-1BB 共刺激,发现 CD28 更优,为 CAR-NK 疗法提供新思路。 在肿瘤治疗的战场上,免疫疗法近年来可谓大放异彩,其中嵌合抗原受体 NK 细胞(CAR-NK)疗法更是潜力无限。它就像给 NK 细胞(自然杀伤细胞 ...
A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...