Expression of all CARs was also similar as measured by western blot and the level of co-expressed eGFP for the fusion constructs. Mapping of sequences involved in recognition of CD19 demonstrated ...

使其表达抗 CD19。然后通过差速离心法分离外泌体，并运用多种检测技术，如动态光散射（Dynamic Light Scattering，DLS）、蛋白质免疫印迹（Western blot）、透射电子显微镜（Transmission Electron Microscopy，TEM）等对其进行表征。此外，还构建了体外 BBB 模型和体内 CNSL 小鼠 ...

By drastically enhancing the effectiveness of CD19 CAR T-cell therapies against lymphoma cells with low or no CD19 antigen expression, Aleta is set to increase B-cell cancer cure rates significantly.

Building on its autologous CD19 CAR-T cell therapy obe-cel, Autolus added a CD22 CAR to create AUTO1/22. The dual mechanism is intended to address a major cause of treatment failure. Thursday ...