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探秘 CBX 家族:CBX2—— 乳腺癌预后新指标与潜在治疗新靶点
在寻找这些 “拼图碎片” 的过程中,科学家们把目光投向了 Polycomb group(PcG,一种表观遗传调控复合物)中的 Chromobox(CBX)蛋白家族。PcG 就像细胞里的 “基因调控大师”,由 polycomb repressive complex 1(PRC1)和 polycomb repressive complex 2(PRC2)这两个主要复合物组成 ...
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