may reduce bone formation by inhibiting OB function. Our data suggest that CCL3 impairs matrix mineralization and suppresses osteocalcin (OCN) production. In particular, CCL3 upregulates ERK ...

THERE is convincing evidence that bone has an orderly morphological and ... consisting essentially of apatite crystals embedded in an organic matrix, might be expected to exhibit piezoelectric ...

These findings reveal how these proteins interact with water and other matrix components to regulate the mechanical behavior of bone. The results open new doors to understanding bone biology and ...