They are now recognized as key metabolites influencing gut and systemic health. By identifying new bile acid metabolites, we are piecing together how these compounds interact with various cellular ...

Analysis of human fetal gallbladder bile provides a more direct assessment of primary hepatic synthesis in utero, but only limited studies have been described. Using HPLC, GLC and mass ...

Bile acids were first described chemically in ... In this next project, we hope to determine how MCBAs are made and how they affect the human gut. The project has three dimensions.

Our gut is a bustling hub of activity, home to trillions of microbes that work together with our bodies to keep us healthy. A recent study explores one fascinating aspect of this partnership: how gut ...

The human body has co-evolved with the beneficial microbes ... One of the most important groups of such molecules is termed bile acids (also known as bile), which are produced from cholesterol ...

Bile is a body fluid produced by the liver that has a digestive and an excretion function. Bile could collect disease biomarkers released from the biliary tract or surrounding tissues, such as the ...

Importantly, BA-MCYs were also detected in human blood samples ... occurring between the gut microbes and the body that is vital for regulating bile acid production," said co-corresponding ...