We know today that Wnt and a handful of other signalling systems (Notch, Hedgehog, TGFβ (transforming growth factor-β)–BMP (bone morphogenetic protein) and receptor tyrosine kinases ...

The aberrant expression of partner of NOB1 homolog (PNO1) is known to promote oncogenesis in the colorectum and the esophagus, but its involvement in ovarian cancer and the mechanisms behind it are ...

The body axis of vertebrates is composed of a serial ... negative feedback inhibitors for each of the Notch, FGF and Wnt pathways (Fig. 3) that potentially account for the robustness of the ...

A growing body of research highlights the crucial role of the Wnt signaling pathway, especially its β-catenin axis, in HCC. This pathway regulates essential processes such as cell proliferation ...