细胞凋亡的基本过程 细胞凋亡（Apoptosis）是一种程序性细胞死亡方式，对于维持机体正常的生理平衡和发育过程至关重要。细胞凋亡主要通过两条途径启动，即内源性途径和外源性途径。 内源性途径又称线粒体途径，当细胞受到内部损伤信号，如 DNA 损伤、氧化 ...

Apoptosis is a form of cell death characterized by a number of morphological changes, including membrane blebbing, cell shrinkage, nuclear and cytoplasmic condensation, and a final breaking up ...

Definitive mechanisms underlying the apparent qualitative changes in CD47 after induction of apoptosis need to be substantiated and will be key to understanding this model.

Researchers have shed new light on how tissues in the body are repaired following the damage and premature death of tissue ...

Researchers have shed new light on how tissues in the body are repaired following the damage and premature death of tissue ...

Scientists use cell death, whether by apoptosis or necrosis, to evaluate the toxicity or effectiveness of substances of interest, including potential therapeutic agents. For example, researchers will ...

Breast cancer is one of the leading causes of mortality among women worldwide. Tumor necrosis factor α-induced protein 3-interacting protein 1 (TNIP1) is a ubiquitin-binding protein that is widely ...

In Ming-Chiu Fung’s immunology lab, Hogan had been investigating how disturbances in the cytoskeletons of cells might contribute to the fragmentation of mitochondria during apoptosis, the most ...

Previous studies revealed a positive correlation between O-GlcNAcylation and tumor growth via the stabilization of target proteins, with O-GlcNAcylation transferase (OGT) being the only enzyme capable ...

Bispecific antibodies have become component in the arsenal of treatments for hematologic malignancies; management of their side effects is crucial to their success.

Discover how combining photodynamic therapy (PDT) with cisplatin enhances lung cancer treatment, promoting tumor cell ...