Protein antigens typically elicit IgG1 ... the typical components of conventional antibodies. This distinct structure was first observed in 1989 during the analysis of both total and fractionated ...

“Protein structure can change in the culture condition — we need to look at their ever-shifting states, not just a snapshot.” Initial images have already shown that antibody structures ...

A study published in December by Duke professor Rohit Singh and his team proposes a new computational model called antibody ...

Antibodies usually have a Y-shaped structure, and these hypervariable regions are located in the tips of the Y, where they detect and bind to foreign proteins, also known as antigens. The bottom ...

A new antibody discovery platform can delve deeper into the mechanisms underlying the processes behind Alzheimer’s and ...

Monoclonal antibodies, or mAbs ... a breakthrough that allowed scientists to investigate the structure and stability of complex proteins like NISTmAb in unprecedented detail.

Using this platform, Aprile and colleagues successfully generated single-domain antibodies (nanobodies) targeting ...

In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that damage brain cells. The process of proteins spontaneously clumping is called ...

That includes DNA, RNA, antibodies, the ligands that bind ... which has just published a blog post on the update. “Experimental protein-structure prediction can take about the length of a ...

New research led by scientists at La Jolla Institute for Immunology (LJI) reveals the workings of a human antibody called mAb ...

Many malignant cancers overexpress a protein called P-cadherin ... The whole P-cadherin/antibody/drug complex is then sent to a structure called the lysosome to be broken down.