Here we discuss why this is the case and how a cultural shift in the biomedical research community could bring the new technologies for creating antibodies and other tailor-designed binding ...

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene ...

The unoccupied antibody binding sites that are usually inversely proportional to the free hormone concentration are quantified using hormone labeled with radioactivity, fluorescence-or ...

The most promising anti-malarial mAbs tested in humans to date bind to the circumsporozoite ... study aimed to find mAbs that target new sites on the sporozoite surface. The research team isolated ...

Biocytogen (HKEX: 02315) and Acepodia (6976:TT), today announced a groundbreaking strategic partnership to jointly assess a dual-payload bispecific antibody-drug conjugate (BsAD2C) program. This press ...

Antibodies usually have a Y-shaped structure, and these hypervariable regions are located in the tips of the Y, where they detect and bind to foreign proteins, also known as antigens. The bottom ...

Antibodies that bind to a previously untargeted portion of ... The researchers in the current study aimed to find mAbs that target new sites on the sporozoite surface. Led by scientists at NIH's ...

In CAR-T therapy, CD19 is now the most extensively used target. It has been confirmed to be effective and safe for the treatment of CLL, B-ALL and B cell lymphoma. FMC63, an IgG2a mouse monoclonal ...

Monoclonal antibodies are, therefore, identical copies of one type of antibody. Antibodies bind to specific antigens on pathogens. This means that only one type of antibody will bind to a matching ...