“The real question is for tissue remodeling—the so-called blood pressure–independent effects of angiotensin II,” says Vanderbilt's Nancy Brown. Angiotensin promotes hypertrophy in the ...

Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu Angiotensin I Asp-Arg-Val-Tyr-Ile-His-Pro-Phe Angiotensin II David W. Cushman In 1967, John Vane, a consultant at The Squibb Institute for Medical Research ...

The effective blockade of angiotensin II effects may therefore help to prevent ... believed to be major determinants in left ventricular remodeling and induction of hypertrophy, fibrosis, and ...

Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...