Researchers at The Wistar Institute's HIV Cure and Viral Diseases Center have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that ...
In RTX-003, a CD25 T reg cell-targeting program, RubrYc used MEMs to identify epitopes and antibodies that enhance antibody directed cellular cytotoxicity (ADCC). This results in T reg cell ...
Gene-modified NK cells expressing CD64 and preloaded with HIV-specific BNAbs target autologous HIV-1–infected CD4+ T cells by ADCC ...
The types and characteristics of FcγRs. Source: Sino Biological Inc. To mediate antibody-dependent cellular cytotoxicity (ADCC), NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA).
NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA) to mediate antibody-dependent cellular cytotoxicity (ADCC). Potentiating therapeutic mAb-mediated CD16 activation of NK cells is an ...
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