In RTX-003, a CD25 T reg cell-targeting program, RubrYc used MEMs to identify epitopes and antibodies that enhance antibody directed cellular cytotoxicity (ADCC). This results in T reg cell ...

Researchers at The Wistar Institute's HIV Cure and Viral Diseases Center have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that ...

NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA) to mediate antibody-dependent cellular cytotoxicity (ADCC). Potentiating therapeutic mAb-mediated CD16 activation of NK cells is an ...

Gene-modified NK cells expressing CD64 and preloaded with HIV-specific BNAbs target autologous HIV-1–infected CD4+ T cells by ADCC ...

Source: Sino Biological Inc. To mediate antibody-dependent cellular cytotoxicity (ADCC), NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA). A new area of cancer immunotherapy is ...